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Circa Group gets green light for sales of its Cyrene bio-based solvent in the EU

Australia-headed biotechnology company Circa Group has announced that it has received authorization from the European Chemicals Agency (ECHA) to manufacture or import up to 100 tonnes per annum of its non-toxic, bio-based and biodegradable solvent called "Cyrene" in the European Union (EU), after receiving REACH Annex VIII approval.

A chiral dipolar aprotic solvent, “Cyrene” was developed in conjunction with the Green Chemistry Centre of Excellence (GCCE) at the University of York in the UK. Cyrene is made in a two-step conversion of waste biomass, produced at Circa’s large-scale prototype plant, built in partnership with Norwegian pulp and paper company Norske Skog in Tasmania, Australia.

Solvent regulation is increasingly focused on restricting hazardous chemicals to manage their risk to people animals and the environment. In the EU, widely used solvents such as NMP, DMF, and DMAc are on the candidate list of Substances of Very High Concern (SVHC) due to their reprotoxicity – adverse effects on sexual function and fertility in males and females.

In addition, a new restriction on NMP was adopted earlier this year, meaning that after May 2020, its use will be further restricted and it will not be able to be manufactured or used in the EU unless operational conditions are maintained to ensure that exposure to workers is below specified levels.

According to Circa Group, its Cyrene solvent provides a safer alternative to these polar aprotic solvents facing regulatory pressure worldwide and is available through Circa’s distributors Merck/Sigma and Will & Co.

Annex VIII authorisation is a major milestone for Cyrene and we are delighted to have been given the go-ahead to sell Cyrene in significantly larger quantities in Europe. Safer solvents are urgently required and with Cyrene, we are also offering a bio-based solution with a unique property set, including viscosity, surface tension, and polarities – making it an exciting new prospect for advanced materials. Our next goal is the registration of Cyrene in the United States and other jurisdictions will soon follow, said Tony Duncan, CEO, and Co-Founder of Circa Group.

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