UK-headed engineering biology firm Ingenza Ltd and Phibro Ethanol – a division of US-headed Phibro Animal Health Corporation – have joined forces to engineer a novel yeast strain that will increase yield in the commercial production of bioethanol under both challenging and conventional environmental conditions, further driving the switch to clean biofuels.
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This latest innovation – arising from a productive and long-standing partnership between the two companies – will help to make this valuable natural resource more widely available for processing into sustainable fuels across a range of industries.
In the United States (US), bioethanol is produced by fermenting typically corn-based biomass with yeast. However, large volumes of enzymes, including glucoamylase (GA) must be added to render the glucose in this feedstock available to the yeast.
In addition, the elevated temperatures generated in the production vessels can stress the yeast, resulting in reduced fermentation performance and, subsequently, lower ethanol yield.
Launch of KinetX
The successful partnership between Ingenza and Phibro sought to solve this issue and led to the introduction of “KinetX” yeast solutions – a highly thermotolerant yeast strain that secretes GA throughout growth and fermentation stages – into the market.
The novel strain was obtained using Ingenza’s proprietary strain construction and adaptive laboratory evolution (ALE) platforms.
According to the company, it offers superior robustness and reliability at higher temperatures while greatly reducing GA addition in comparison to traditional yeasts, bringing significant financial benefits to bioethanol producers.
Increasing the efficiency of bioethanol production is crucial to boost the commercial viability of biofuels as green alternatives to the fossil fuels we currently rely on. We are strongly committed to Phibro’s goals, and we are confident our ongoing collaboration will play a leading role in reducing the carbon footprint of the transportation sector, helping to achieve global sustainability targets, said Dr Leonardo Magneschi, Head of Molecular Biology at Ingenza.
Additional next-generation yeast lines in the KinetX portfolio will shortly debut on the international market alongside other programs incorporating other novel technologies to deliver even higher bioethanol yields.
Ingenza’s expertise in custom-built strain development, ALE, high throughput screening, and technology transfer has been key to the successful implementation and scale-up of our industry-leading products. We look forward to working with Ingenza in the future to implement additional innovations that will further support the worldwide transition to environmentally friendly, bio-based fuels, said Dr Stephanie Gleason, Director of Technology at Phibro.
