All subjects
Biofuels & Oils

Ingenza and Phibro Ethanol develop novel yeast strain to increase ethanol yield

Ingenza and Phibro Ethanol develop novel yeast strain to increase ethanol yield
Ingenza Ltd is an engineering biology company with an extensive and unique range of proprietary enabling technologies in microbial strain and mammalian cell-line engineering, protein production, fermentation, and bioprocess development with state-of-the-art facilities in Edinburgh, Scotland (photo courtesy Ingenza).

UK-headed engineering biology firm Ingenza Ltd and Phibro Ethanol – a division of US-headed Phibro Animal Health Corporation – have joined forces to engineer a novel yeast strain that will increase yield in the commercial production of bioethanol under both challenging and conventional environmental conditions, further driving the switch to clean biofuels.

An error occurred

You are logged in as subsbriber at Bioenergy International, but something is wrong.

On your profile you can see what subscriptions you have access to and more information.

Is some of the information wrong – please contact our customer service.

Please reload the page

We could not ascertain if you are logged in or not. Please reload this page.
Bioenergy International premium

Do you want to read the whole article?

Only logged in payed subscribers can read all contents on
As an subscriber you get:
  • Six editions per year
  • Full access to all digital content
  • The E-magazine Bioenergy international
  • And more ...

This latest innovation – arising from a productive and long-standing partnership between the two companies – will help to make this valuable natural resource more widely available for processing into sustainable fuels across a range of industries.

In the United States (US), bioethanol is produced by fermenting typically corn-based biomass with yeast. However, large volumes of enzymes, including glucoamylase (GA) must be added to render the glucose in this feedstock available to the yeast.

In addition, the elevated temperatures generated in the production vessels can stress the yeast, resulting in reduced fermentation performance and, subsequently, lower ethanol yield.

Launch of KinetX

The successful partnership between Ingenza and Phibro sought to solve this issue and led to the introduction of “KinetX” yeast solutions – a highly thermotolerant yeast strain that secretes GA throughout growth and fermentation stages – into the market.

The novel strain was obtained using Ingenza’s proprietary strain construction and adaptive laboratory evolution (ALE) platforms.

According to the company, it offers superior robustness and reliability at higher temperatures while greatly reducing GA addition in comparison to traditional yeasts, bringing significant financial benefits to bioethanol producers.

Increasing the efficiency of bioethanol production is crucial to boost the commercial viability of biofuels as green alternatives to the fossil fuels we currently rely on. We are strongly committed to Phibro’s goals, and we are confident our ongoing collaboration will play a leading role in reducing the carbon footprint of the transportation sector, helping to achieve global sustainability targets, said Dr Leonardo Magneschi, Head of Molecular Biology at Ingenza.

Additional next-generation yeast lines in the KinetX portfolio will shortly debut on the international market alongside other programs incorporating other novel technologies to deliver even higher bioethanol yields.

Ingenza’s expertise in custom-built strain development, ALE, high throughput screening, and technology transfer has been key to the successful implementation and scale-up of our industry-leading products. We look forward to working with Ingenza in the future to implement additional innovations that will further support the worldwide transition to environmentally friendly, bio-based fuels, said Dr Stephanie Gleason, Director of Technology at Phibro.

Most read on Bioenergy International

Get the latest news about Bioenergy

Subscribe for free to our newsletter
Sending request
I accept that Bioenergy International stores and handles my information.
Read more about our integritypolicy here